This repository contains scripts and jupyter notebooks used to analyze laboratory evolution data, infer residue-residue interactions, and determine 3-dimensional structure. The project is explained in detail in our recent publication:

Michael A Stiffler^_*#, Frank J Poelwijk^_*#, Kelly P Brock, Richard R Stein, Adam Riesselman, Joan Teyra, Sachdev Sidhu, Debora S Marks, Nicholas P Gauthier^_@#, Chris Sander^_@#. (2019). Protein Structure from Experimental Evolution. Cell Systems, in press.

* Joint first authors
@ Joint last authors
# Email to 3Dseq.research@gmail.com reaches the principal authors

• See README.md or README.txt files for a description of the scripts in each folder.
• Accessory files are available from https://api.evcouplings.org/3Dseq/